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| Product Category: | Knockdown Validated Polyclonal Antibody |
| Synonyms: | Prohibitin; Epididymis Secretory Sperm Binding Protein Li 54e; Epididymis Luminal Protein 215; HEL-S-54e; HEL-215; PHB1 |
| UniProt Entry: | P35232 |
| NCBI Gene Entry: | 5245 |
| Molecular Weight: | 32 kDa |
| Clonality: | Rabbit polyclonal antibody |
| Species Reactivity: | Human |
| Applications: | WB |
| Recommended Dilution: | WB 1:1000 |
| Immunogen: | Recombinant fragment of human PHB |
| Isotype: | Rabbit IgG |
| Storage Buffer: | Supplied in PBS (pH 7.5) containing 50 µg/ml BSA, 50% glycerol, and 0.01% sodium azide |
| Storage: | At –20°C |
| Background: | PHB gene is evolutionarily conserved, and its product is proposed to play a role in human cellular senescence and tumor suppression. Antiproliferative activity is reported to be localized to the 3' UTR, which is proposed to function as a trans-acting regulatory RNA. Several pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants. |
| Documents: | Please contact us to request the manual |
